England have called up uncapped players Mooen Ali and Stephen Parry for the tour of the West Indies and the ICC World Twenty20 with Harry Gurney picked to tour the Caribbean.
Alastair Cook will miss the tour of the West Indies and Stuart Broad will lead the side in three One-Day Internationals and three Twenty20 Internationals.
Eoin Morgan has been named as Broad's vice-captain and England have picked a young squad as they begin a rebuilding process.
With Cook rested and Kevin Pietersen, Graeme Swann and Jonathan Trott unavailable for different reasons, England have opted to ring the changes.
James Anderson remains out of contention while from the players that were named in the squad for the Twenty20 series in Australia, Danny Briggs, Steven Finn, Boyd Rankin and Chris Woakes have been left out.
ENGLAND'S NEW CALL-UPS
Worcestershire batsman Moeen Ali bowls occasional off-spin. Scored 1,420 first-clas runs and played for England Lions against Australia in 2013. Cousin of ex-England international Kabir.
Parry is a left-arm spinner who plies his trade with Lancashire. Took 11 one-day wickets at 19.63 in 2013.
Gurney is a left-arm fast bowler who plays for Nottinghamshire. He moved from Leicestershire to Trent Bridge in 2012, following the path travelled by Broad and James Taylor.
"Both Moeen and Stephen have been very consistent performers for Worcestershire and Lancashire and both counties and their coaching staffs, must take credit for their continued progress," National Selector James Whitaker said.
"Harry Gurney, under the guidance of the excellent coaches at Trent Bridge, has performed well for Nottinghamshire in limited overs cricket - showing good control with the white ball and, as a left arm quick, brings some variety to the tour party.
"England have won the ICC World Twenty20 before - in 2010 in the Caribbean - and this group has an exciting mix of youth and Twenty20 experience and I am sure with good preparation, desire and determination they will be able to produce an exciting brand of cricket."
England ODI/T20I squad to play in the West Indies: Stuart Broad (captain), Eoin Morgan (vice-captain), Moeen Ali, Ravi Bopara, Tim Bresnan, Jos Buttler, Jade Dernbach, Harry Gurney, Alex Hales, Chris Jordan, Michael Lumb, Stephen Parry, Joe Root, Ben Stokes, James Tredwell, Luke Wright
England ICC WT20 squad: Stuart Broad (captain), Eoin Morgan (vice-captain), Moeen Ali, Ravi Bopara, Tim Bresnan, Jos Buttler, Jade Dernbach, Alex Hales, Chris Jordan, Michael Lumb, Stephen Parry, Joe Root, Ben Stokes, James Tredwell, Luke Wright
England in the West Indies
25th February: Vice-Chancellor's XI v England XI, Antigua
28th February: 1st ODI, Antigua
2nd March: 2nd ODI, Antigua
5th March: 3rd ODI, Antigua
9th March: 1st T20I, Barbados
11th March: 2nd T20I, Barbados
13th March: 3rd T20I, Barbados
England in the ICC WT20, Bangladesh
22nd March: England v New Zealand
27th March: England v Sri Lanka
29th March: England v South Africa
31st March: England v Qualifier
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