Eoin Morgan will captain a young England team against the country of his birth - Ireland - in a one-off One-Day International in Clontaft on 25th August.
The England selectors have decided to rest a number of senior players, calling up Leicestershire batsman James Taylor, Yorkshire wicket-keeper Jonathan Bairstow and Durham pair Scott Borthwick, Ben Stokes for the first time.
Graham Onions is the third Durham player in the squad while Jonathan Trott has been added to the squad after making a good recovery from the shoulder injury that kept him out of the third and fourth Tests against England.
Team Director Andy Flower will also be taking a rest, along with the likes of Alastair Cook, Ian Bell, Stuart Broad and James Anderson, with assistant coach Richard Halsall standing in.
"The squad we're looking to take to Ireland involves a number of exciting young England players as we rest several players currently involved in the npower Test series against India," national selector Geoff Miller said.
"By resting several players that have played international cricket since the start of the summer the opportunity has arisen for a number of talented up and coming players to continue their development on the international stage. We know from previous encounters that Ireland are a tough ODI outfit and we'll be fielding a very strong England side that will need to play well.
"We're also presented with the opportunity to provide Eoin Morgan with further leadership experience and I know he is very much looking forward to assuming the captaincy and developing his leadership credentials while in charge of a young England squad.
"Jonathan Trott has made continued improvement from his shoulder injury and will be available for selection."
England ODI squad: Eoin Morgan (captain), Jonathan Bairstow, Ravi Bopara, Scott Borthwick, Jade Dernbach, Steven Finn, Craig Kieswetter, Graham Onions, Samit Patel, Ben Stokes, James Taylor, Jonathan Trott, Chris Woakes
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